America's #1 Hand Cream Brand*

Original Jar

Hand Cream

Original Tube

Hand Cream

Pumpable Hand Cream

Hand Cream

Intense Renewal

Hand Cream

Night Treatment

Hand Cream

Pain Relief

Hand Cream

DAILY ESSENTIAL HYDRATION

Lotion

12 oz Pump

Hand Representative Photos: Before and after hand images from two week usage period. Cream was applied before bed and three times daily.

How Working Hands Works

The Science Behind Healthier Skin

O'Keeffe's doesn't just mask symptoms – it actively works to improve your skin health.

Instant Moisture Boost

Our unique formula immediately increases the moisture content of your skin.

Protective Barrier

We create a protective layer on the skin's surface to lock in that moisture.

Lasting Hydration

This barrier helps prevent further moisture loss, keeping your hands softer and healthier for longer.

"As a healthcare worker and mom, I wash my hands a ton and my hands get so dry and cracked. This is hands down the most effective cream I have tried."

"I wash and sanitize my hands at least a hundred times a day. Dryness and peeling are not fun. I love Working Hands because it applies quickly and absorbs into the skin without feeling greasy or oily."

I finally found hand cream that works on my hands! Working in the medical field, using soaps and gloves had my hands extremely dry. Thank you very much for making this amazing hand cream 🙌🏼

"I have been battling dry skin problems for 10 years. I’m a nurse and wash my hands up to 50 x a day. I used O’Keeffe’s Working Hands and now and my skin looks and feels wonderful. Thank You."

FAQS

Here are a few common questions

Is Working Hands safe for sensitive skin?

While our formula is designed to be gentle, if you have particularly sensitive skin, we recommend doing a patch test first.

How long before I see results?

While individual results may vary, many users report improvement within a few days of regular use.

Can I use Working Hands on my feet?

Yes, although for optimal foot care, we recommend our Healthy Feet cream, specifically formulated for foot skin.

How often should I apply Working Hands?

For best results, apply daily, especially after bathing and before bed. In harsh conditions, you may apply more frequently.

100%

Our Promise To You: Guaranteed Relief Or Your Money Back

We stand behind every product we make. If you're not completely satisfied, we'll refund 100% of your purchase price.
Click here for terms.

Where To Buy

Available Pretty Much Everywhere

A 25+ Year Heritage of Guaranteed Relief

So You Can Keep Going

O'Keeffe's began with a daughter's love for her hardworking father. What started in a kitchen to help one rancher's dry, cracked hands has grown into a trusted brand, helping millions find relief from extreme dryness.